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Paget's Disease Diagnostic
New polymorphisms in a gene panel that explain susceptibility to Paget’s disease of bone (PDB) have been identified. The discovery should provide a test for patient groups at risk of developing the disease, and therefore provide for early intervention in a disease that affects up to 2% of individuals of European ancestry aged 55 and above. Opportunity 373
Cognitive training for babies and toddlers
MRC-funded scientists in the Babylab at the Centre for Brain and Cognitive Development in London have developed novel computer-based games for use in cognitive training for babies and toddlers. In controlled tests, a short training period led to significant improvements in infants’ concentration skills. Opportunity 467
Screening of polymerases in emulsions and selected polymerases
An emulsion based technique (“High throughput screening in emulsions”) for selection of polymerases exhibiting desired characteristics. The method can be adapted to select polymerases under various conditions, to meet the constant need for new enzymes with different properties from the wild type. Selected polymerases developed by the method are also available for licensing. Opportunity 243
Molecular Copy Number Counting (MCC)
A robust and simple PCR-based method for measuring gene copy number. Genetic copy number variations (CNV) are often associated with genetic disorders, degenerative diseases and cancer, and the method has applications in personalised treatment of cancer, diagnosis of genetic disease and fertility treatment. Opportunity 245
Novel low-cost affinity reagent platform technology
A novel affinity technology that can efficiently staple together, capture or immobilise multiple proteins, useful as a platform technology with a vast number of potential applications including use as a research tool, as part of a diagnostic platform or for in vivo drug delivery. Opportunity 306
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