Are you a chemistry or biochemistry student looking for a ‘year in industry’ placement in interdisciplinary drug discovery?

MRC Technology, a medical research charity, is offering a one year placement opportunity for an undergraduate within the chemistry section of our Antibody-Drug Conjugate (ADC) group, starting September 2017. The placement offers the chance to gain experience in generating and analysing the structure and properties of novel ADCs, synthetic molecules that combine antibodies with therapeutically active small molecules. Specific goals for this project will include the assessment and optimisation of a variety of conjugation methodologies and the systematic analysis of the conjugates produced in both form and function.

This work is highly interdisciplinary and would suit anyone with skills in chemistry, biochemistry or mass spec analysis, with an interest in working across all three of these areas. This placement will provide the opportunity to learn skills in analytical techniques, molecular biology and organic chemistry in an exciting and challenging environment.

The successful applicant will become a member of the cross discipline ADC project team. The student will be expected to fully participate in the team and although directly supervised by one of the experienced team members, they will find they are routinely working with a number of both chemistry and biology scientists. Regular verbal presentations of experimental results and conclusions will be given by the student to the project team and to chemistry management, and the student will be expected to maintain high quality electronic lab notebook records of their research.

Any reasonable requirements set by the student’s institution for work towards the degree course will be supported.  During the placement year, at least one area of the research will be identified as suitable for any written project requirements in support of the student’s degree submission.

MRC Technology’s Centre for Therapeutics Discovery (CTD) undertakes small molecule and therapeutic antibody drug discovery against novel targets in collaboration with academic groups across the UK and the world. Based in research laboratories in Stevenage, CTD currently consists of around 75 scientists. This number includes the chemistry department of 24 scientists, who work on early stage small molecule medicinal chemistry programs and small molecule antibody conjugation strategies.

MRC Technology offers 10 student placements a year – 3 in chemistry and 7 in biology, with placements starting in early September and running for 11.5 months.

Final acceptance onto a placement position will depend on a satisfactory outcome of a medical assessment. The contracted role is Monday – Friday with some flexibility around working pattern, and the students will be expected to respond to any reasonable requests to work outside normal hours in order to achieve specific objectives.The present rate of pay for industrial placements is approximately £18,000 per annum.

It is MRCT’s policy to employ individuals on the basis of their suitability for the work to be performed and their potential for development, regardless of age, sex, race, colour, nationality, ethnic or national origin, disability, marital status, pregnancy or maternity, sexual orientation, gender reassignment, religion or belief.

To apply please email your CV and covering letter, containing details of you current course, to: recruitment@tech.mrc.ac.uk or by post to Recruitment, MRC Technology, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX (electronic applications preferred).

Closing date: 13 April 2017

How to apply

Email: recruitment@tech.mrc.ac.uk

Edinburgh

Competitive Salary and Benefits

 MRC Technology (MRCT) is an independent life science medical research charity committed to drastically improving positive patient outcomes everywhere. As a champion for human health, MRCT partners with academic, biotechnology, pharmaceutical and charity organisations to translate promising medical research into significant new treatments for patients.

MRC Technology’s Centre for Diagnostic Development (CDD) operates at the interface between academic research and the Diagnostic industry. It offers collaborative diagnostic assay development and validation, helping translate early stage diagnostic research through to its commercial exploitation and its use in the clinic.

CDD are currently focused on developing molecular diagnostics where there is an unmet clinical need in areas such as oncology, infectious disease and inflammatory disease. The facility has state of the art data capture and management systems and uses the latest technological platforms such as Next Gen Sequencing and multiplex qPCR to design and develop innovative molecular diagnostics. The team will shortly be relocating to a large facility in the Edinburgh BioQuarter, so this is an exciting time to help grow and contribute to CDD’s success.

We are looking for an enthusiastic and motivated individual, ideally educated to HND or BSc level. Your primary role will be to support the laboratory activities but there will be the opportunity to be involved with individual projects where required. Training will be provided.

Ideally you should have experience working in a laboratory environment, in the use of scientific equipment (e.g. PCR thermal cyclers, centrifuges) and be familiar with standard molecular biology laboratory techniques (e.g. DNA and RNA manipulation). You will participate in the calibration and maintenance of equipment, ordering of consumables and general housekeeping. A good working knowledge of Microsoft Office software is required. You should be able to demonstrate good attention to detail and excellent communication skills. You will be expected to work under a quality management system.

Your salary will be determined by qualifications and experience. In addition MRCT offers a Defined Contribution pension scheme, Private Health Insurance, a flexible benefits scheme and 31 days paid holiday per year.

It is MRCT’s policy to employ individuals on the basis of their suitability for the work to be performed and their potential for development, regardless of age, sex, race, colour, nationality, ethnic or national origin, disability, marital status, pregnancy or maternity, sexual orientation, gender reassignment, religion or belief.

To apply please email your CV and covering letter to: recruitment@tech.mrc.ac.uk

Closing date: 2nd April 2017

How to apply

Email: recruitment@tech.mrc.ac.uk

MRC Technology (MRCT) is an independent life science medical research charity committed to drastically improving positive patient outcomes everywhere. As a champion for human health, MRCT partners with academic, biotechnology, pharmaceutical and charity organisations to translate promising medical research into significant new treatments for patients.

Our Technology Transfer division (TT) collaborates with and provides services to a range of clients including charities worldwide, academic research institutes, the Medical Research Council (MRC) and MRCT’s own in-house research and development functions:  its Centre for Therapeutics Discovery (CTD) and Centre for Diagnostic Development (CDD) which develop potential new drugs and diagnostics respectively in collaboration with its academic and industry partners.

The purpose of this role is to support internal and external clients to identify protectable IP with potential for translation, manage the IP protection process, and ultimately market and commercialisation.  The role will also involve undertaking IP portfolio audits and providing advice on commercialisation strategies for the charity sector, as well as working with internal project teams to develop MRCT’s drug discovery projects to a point at which they are ready for partnering with industry.

The Senior Business Manager will have line management responsibilities and will be expected to develop and manage the performance of a small team of Business Managers.

The successful candidate will ideally:

  • be qualified to PhD level (or have equivalent experience) in a relevant scientific subject.
  • have the ability to quickly grasp new scientific concepts and technologies and to identify where there may be commercial potential, how this could best be realised and experience of partnering and commercialising such technology.
  • have in-depth knowledge of the pharmaceutical drug discovery and development process and of the commercial landscape of the pharmaceutical industry
  • preferably, have line management experience, preferably of technology transfer, patent  or business development professionals.
  • have a proven record of high level commercial thinking with experience of shaping and implementing a complex business strategy.
  • have the ability to communicate orally and in writing, effectively and credibly with a range of stakeholders, including scientists, industry and with colleagues.
  • have experience of IP management in an academic or commercial environment which should include identification, due diligence, and protection of IP.
  • have a successful track record of handling commercial negotiations.
  • have project management experience including the ability to manage and progress multiple projects efficiently.
  • have the ability to work independently and proactively, but also as part of teams where there may be multiple expectations and drivers.

Your salary will be determined by qualifications and experience. In addition, MRCT offers a defined contribution pension scheme, private health insurance, a flexible benefits scheme and 31 days paid holiday per year.

MRCT is committed to the principles and practices of equal opportunities in employment and encouraging the establishment of a diverse workforce. This includes creating a culture that fully reflects its commitment to equal opportunities for all.

It is MRCT’s policy to employ individuals on the basis of their suitability for the work to be performed and their potential for development, regardless of age, sex, race, colour, nationality, ethnic or national origin, disability, marital status, pregnancy or maternity, sexual orientation, gender reassignment, religion or belief.

To apply, please email your CV and covering letter explaining why you want to work for MRC Technology’s Technology Transfer division to: recruitment@tech.mrc.ac.uk or by post to Recruitment, MRC Technology, Lynton House, 7-12 Tavistock Square, London, WC1H 9LT (electronic applications preferred).

Closing date:  29 March 2017

How to apply

Email: recruitment@tech.mrc.ac.uk